Tworek works on the international history of news. Her work rethinks the role of information and news in historical processes by examining the political, economic, technological, and legal networks that influenced the creation of news from global events. Her current book project focuses on news agencies as the nexus of modern news collection and dissemination. Her further research interests include media, international organizations, intellectual property, and higher education.

In October 2012, she launched the UN History Project website to provide materials for researching and teaching the history of international organizations. She has published in journals including Journalism Studies, Historical Social Research, German History, and Enterprise & Society. She has also written and spoken on higher education for The Atlantic and on KCRW as well as on news for a variety of publications.

She received her BA (Hons) in Modern and Medieval Languages with a double first from Cambridge University in 2006 and earned her PhD in History from Harvard University in 2012. Her dissertation received the Herman E. Krooss Prize for best dissertation in business history. She currently holds the position of Assistant Director of Undergraduate Studies and Lecturer on History in the Harvard History Department.